Fish in Chips: Molecular Typing of Her-2 Biomarker for Rapid and Low Cost Cancer Diagnosis and Treatment Selection

نویسندگان

  • Karla Perez-Toralla
  • Irena Draskovic
  • François-Damien Delapierre
  • Sandrine Miserere
  • Laurent Malaquin
  • Jean-Louis Viovy
  • Guillaume Mottet
چکیده

We have recently developed a novel microfluidic system based on self-assembled magnetic particles for cell sorting. This device is able to capture very rare cells, such as circulating tumour cells (CTC), in biological samples (blood, bone marrow). The captured cells can be analysed by bright field and fluorescence microscopy at high magnification [1]. We are now interested in new microfabrication techniques using thermoplastic polymers that allow the implementation of an automated FISH platform to perform high content genomic analyses of cancer cells inside the chip.

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تاریخ انتشار 2010